MusthInsider

Latest On (BOLD):

Updated on: January 01, 1970

Date/Time	Type	Description	Signal
2020-07-28 12:19 EST	Financials	Company financials have been released.	Neutral
2020-07-23 16:27 EST	Financials	Company financials have been released.	Neutral
2020-07-10 08:17 EST	Financials	Company financials have been released.	Neutral
2020-05-31 16:44 EST	Financials	Company financials have been released.	Neutral
2020-05-03 08:19 EST	Financials	Company financials have been released.	Neutral
2020-04-07 12:16 EST	Financials	Company financials have been released.	Neutral
2020-04-07 00:22 EST	Financials	Company financials have been released.	Neutral
2020-02-29 23:19 EST	Financials	Company financials have been released.	Neutral
2020-02-28 23:16 EST	Financials	Company financials have been released.	Neutral
2020-02-28 03:18 EST	Financials	Company financials have been released.	Neutral
2020-02-21 23:13 EST	Financials	Company financials have been released.	Neutral
2020-02-07 23:15 EST	Financials	Company financials have been released.	Neutral
2020-02-06 23:14 EST	Financials	Company financials have been released.	Neutral
2020-01-29 23:15 EST	Financials	Company financials have been released.	Neutral
2020-01-28 03:18 EST	Earnings	Earnings have been released on March 8, 2018, with -$0.82 earnings per share.	Buy
2020-01-28 03:18 EST	Earnings	Earnings have been released on March 9, 2017, with -$0.91 earnings per share.	Sell
2020-01-28 03:18 EST	Earnings	Earnings have been released on November 7, 2019, with -$1.00 earnings per share.	Buy
2020-01-16 23:18 EST	Financials	Company financials have been released.	Neutral
2020-01-10 18:32 EST	Insider Trade	Matthew R Patterson has directly acquired 11,666 shares and currently holds 261,458 shares.	Buy
2020-01-10 18:32 EST	Insider Trade	Matthew R Patterson has directly acquired 11,824 shares and currently holds 249,792 shares.	Buy
2020-01-10 18:32 EST	Insider Trade	Matthew R Patterson has directly acquired 74,297 shares and currently holds 237,968 shares.	Buy
2020-01-10 18:32 EST	Insider Trade	Matthew R Patterson has directly acquired 64,751 shares and currently holds 163,671 shares.	Buy
2020-01-10 18:32 EST	Insider Trade	Thomas P Soloway has directly acquired 6,219 shares and currently holds 183,384 shares.	Buy
2020-01-10 18:32 EST	Insider Trade	Thomas P Soloway has directly acquired 144,669 shares and currently holds 177,165 shares.	Buy
2019-12-27 16:54 EST	Insider Trade	LOUIS G LANGE has disposed of 1,000 shares indirectly via Amygdala Lange Trust.	Sell
2019-12-27 16:53 EST	Insider Trade	LOUIS G LANGE has directly disposed of 10,000 shares and currently holds 265,799 shares.	Sell
2019-12-16 23:15 EST	Financials	Company financials have been released.	Neutral
2019-12-16 23:14 EST	Analyst Rating	The Analyst Target Price has increased from $56.58 to $58.75.	Neutral
2019-12-16 18:32 EST	Insider Trade	Natalie C. Holles has directly acquired 14,895 shares and currently holds 193,367 shares.	Buy
2019-12-16 18:32 EST	Insider Trade	Natalie C. Holles has directly acquired 6,891 shares and currently holds 178,472 shares.	Buy
2019-12-16 18:32 EST	Insider Trade	Natalie C. Holles has directly acquired 74,117 shares and currently holds 171,581 shares.	Buy
2019-12-16 18:32 EST	Insider Trade	Natalie C. Holles has directly acquired 5,715 shares and currently holds 97,464 shares.	Buy
2019-12-16 18:32 EST	Insider Trade	Natalie C. Holles has directly acquired 45,726 shares and currently holds 91,749 shares.	Buy
2019-12-16 18:32 EST	Insider Trade	Thomas P Soloway has directly acquired 41,321 shares and currently holds 53,954 shares.	Buy
2019-12-06 07:08 EST	Analyst Rating	The Analyst Target Price has increased from $55.25 to $56.58.	Neutral
2019-12-04 07:08 EST	Analyst Rating	The Analyst Target Price has increased from $42 to $55.25.	Neutral
2019-12-03 12:57 EST	News	UniQure and ViewRay among healthcare gainers; Cara Therapeutics among losers	N/A
2019-12-03 12:57 EST	News	CBL, CARA, VRAY and BOLD among midday movers	N/A
2019-12-03 11:03 EST	News	Healthcare dominates premarket gainers	N/A
2019-12-02 23:49 EST	News	Astellas Pharma to buy Audentes Therapeutics for $60/share	N/A
2019-11-27 23:14 EST	Financials	Company financials have been released.	Neutral
2019-11-26 23:14 EST	Financials	Company financials have been released.	Neutral
2019-11-22 23:12 EST	Financials	Company financials have been released.	Neutral
2019-11-15 23:13 EST	Financials	Company financials have been released.	Neutral
2019-11-13 10:43 EST	Insider Trade	Matthew R Patterson has directly disposed of 14,426 shares and currently holds 113,394 shares.	Sell
2019-11-13 10:43 EST	Insider Trade	Matthew R Patterson has directly acquired 14,426 shares and currently holds 127,820 shares.	Buy
2019-11-11 03:09 EST	Analyst Rating	The Analyst Target Price has decreased from $43 to $42.	Neutral
2019-11-10 22:49 EST	News	Audentes Therapeutics, Inc. (BOLD) CEO Matt Patterson on Q3 2019 Results - Earnings Call Transcript	N/A
2019-11-08 23:10 EST	Financials	Company financials have been released.	Neutral
2019-11-08 07:08 EST	Earnings Estimate	An EPS average of -$1.10 is estimated for the quarter ending on March 31, 2020.	Sell

About (BOLD):

N/A

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General

Name
Symbol
Type
Exchange
Currency
Country
Last Split Date

(BOLD) Dividend Calendar:

pays out 0% of its earnings out as a dividend.

Ex-Dividend Date	Payment Date	Record Date	Declared Date	Amount

(BOLD) Earnings History:

Companies typically report earnings on both a quarterly and annual basis. Earnings reported that deviate from analysts' expectations can have a large impact on a stock's price.

Quarter Date	Report Date	Actual Revenue	Reported EPS	EPS Estimate	Deviation from Estimate
2019-09-30	2019-09-30	$N/A	-$1.00	-$1.07	6.54%
2019-06-30	2019-06-30	$N/A	-$1.01	-$1.04	2.88%
2019-03-31	2019-03-31	$N/A	-$1.13	-$0.89	-26.97%
2018-12-31	2019-02-27	$N/A	-$0.84	-$0.91	7.69%
2018-09-30	2018-11-06	$N/A	-$0.97	-$0.88	-10.23%
2018-06-30	2018-08-08	$N/A	-$0.85	-$0.78	-8.97%
2018-03-31	2018-05-10	$N/A	-$0.74	-$0.80	7.5%
2017-12-31	2018-03-08	$N/A	-$0.82	-$0.91	9.89%
2017-09-30	2017-11-15	$N/A	-$0.88	-$0.89	1.12%
2017-06-30	2017-08-10	$N/A	-$0.87	-$0.79	-9.81%
2017-03-31	2017-05-11	$N/A	-$0.83	-$0.92	9.78%
2016-12-31	2017-03-09	$N/A	-$0.91	-$0.75	-21.33%
2016-06-30	2016-09-01	$N/A	-$6.43	-$1.33	-383.46%

(BOLD) Company Financial Statements:

Financial statements are reports prepared by a company's management to present their financial performance and position at a point in time. A general-purpose set of financial statements usually includes a balance sheet, income statements, and statement of cash flows.

Income Statement:

Date
Research Development
Income Before Tax
Selling General Administrative
Gross Profit
Ebit
Operating Income
Income Tax Expense
Total Revenue
Cost of Revenue
Total Other Income Expense Net
Net Income From Continuing Operations
Net Income Applicable to Common Shares

Cash Flow:

Date
Investments
Change to Liabilities
Total Cash Flow from Investing Activities
Net Borrowings
Total Cash Flow from Financial Activities
Change to Operating Activities
Change in Cash
Total Cash from Operating Activities
Depreciation
Other Cash Flow from Investing Activities
Change to Inventory
Change to Account Receivables
Other Cash Flow from Financing Activities
Change to Net Income
Capital Expenditures

Balance Sheet:

Date
Total Liabailities
Total Stockholder Equity
Other Current Liabilities
Total Assets
Common Stock
Other Current Assets
Retained Earnings
Other Liabilities
Other Assets
Cash
Total Current Liabilities
Other Stockholder Equity
Property, Plant & Equipment
Total Current Assets
Long Term Investments
Net Tangible Assets
Short Term Investments
Long Term Debt
Inventory
Accounts Payable

(BOLD) Chart:

(BOLD) News:

Below you will find a list of latest news for (BOLD) from major news sources. You can filter the results to only show news from a specific source.

No recent news available

(BOLD) Options:

A stock option is a contract between two parties in which the stock option buyer (holder) purchases the right (but not the obligation) to buy/sell 100 shares of an underlying stock at a predetermined price from/to the option seller (writer) within a fixed period of time.

Expiration Date	Strike	Last Price	Type	Volume	Open Interest	Implied Volatility	In The Money	Change	Change Percent

(BOLD) SEC Filings:

An SEC filing is a financial statement or other formal document submitted to the U.S. Securities and Exchange Commission (SEC). Public companies, certain insiders, and broker-dealers are required to make regular SEC filings.

Date	Form Type	Form Name	Link
2020-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000110465920021813/0001104659-20-021813-index.htm
2018-09-11	UPLOAD	SEC-generated letter	https://www.sec.gov/Archives/edgar/data/1628738/000000000018028122/0000000000-18-028122-index.htm
2019-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000008025519002704/0000080255-19-002704-index.htm
2019-02-08	SC 13G	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000021545719006756/0000215457-19-006756-index.htm
2018-09-10	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000031506618002322/0000315066-18-002322-index.htm
2018-10-10	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000031506618002415/0000315066-18-002415-index.htm
2019-02-13	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000031506619000905/0000315066-19-000905-index.htm
2019-11-12	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000031506619001760/0000315066-19-001760-index.htm
2020-02-05	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000083423720004619/0000834237-20-004619-index.htm
2019-02-12	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000090221919000133/0000902219-19-000133-index.htm
2020-01-07	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000090221920000003/0000902219-20-000003-index.htm
2019-09-16	SC 13G	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000093041319002492/0000930413-19-002492-index.htm
2019-02-13	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000110465919007933/0001104659-19-007933-index.htm
2020-02-11	SC 13G	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000110465920016339/0001104659-20-016339-index.htm
2020-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000110465920021676/0001104659-20-021676-index.htm
2020-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000110465920021813/0001104659-20-021813-index.htm
2018-10-29	SC 13G	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000114420418055839/0001144204-18-055839-index.htm
2019-02-14	SC 13G	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000114420419008063/0001144204-19-008063-index.htm
2019-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000114420419008387/0001144204-19-008387-index.htm
2019-02-13	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000117266119000429/0001172661-19-000429-index.htm
2020-02-14	SC 13G/A	Statement of acquisition of beneficial ownership by individuals	https://www.sec.gov/Archives/edgar/data/1628738/000117266120000840/0001172661-20-000840-index.htm
2018-10-09	424B5	Prospectus [Rule 424(b)(5)]	https://www.sec.gov/Archives/edgar/data/1628738/000119312518295967/0001193125-18-295967-index.htm
2018-10-11	424B5	Prospectus [Rule 424(b)(5)]	https://www.sec.gov/Archives/edgar/data/1628738/000119312518297649/0001193125-18-297649-index.htm
2019-12-03	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000119312519304554/0001193125-19-304554-index.htm
2019-12-03	SC TO-C	Written communication relating to an issuer or third party	https://www.sec.gov/Archives/edgar/data/1628738/000119312519304603/0001193125-19-304603-index.htm
2019-12-03	SC14D9C	Written communication relating to third party tender offer	https://www.sec.gov/Archives/edgar/data/1628738/000119312519304608/0001193125-19-304608-index.htm
2019-12-04	SC TO-C	Written communication relating to an issuer or third party	https://www.sec.gov/Archives/edgar/data/1628738/000119312519306187/0001193125-19-306187-index.htm
2019-12-09	SC TO-C	Written communication relating to an issuer or third party	https://www.sec.gov/Archives/edgar/data/1628738/000119312519309195/0001193125-19-309195-index.htm
2019-12-16	SC TO-T	Tender offer statement by Third Party	https://www.sec.gov/Archives/edgar/data/1628738/000119312519314292/0001193125-19-314292-index.htm
2019-12-16	SC 14D9	Solicitation, recommendation statements	https://www.sec.gov/Archives/edgar/data/1628738/000119312519314312/0001193125-19-314312-index.htm
2019-12-16	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000119312519314351/0001193125-19-314351-index.htm
2019-12-30	SC TO-T/A	Tender offer statement by Third Party	https://www.sec.gov/Archives/edgar/data/1628738/000119312519325139/0001193125-19-325139-index.htm
2019-12-30	SC 14D9/A	Solicitation, recommendation statements	https://www.sec.gov/Archives/edgar/data/1628738/000119312519325174/0001193125-19-325174-index.htm
2020-01-07	SC TO-T/A	Tender offer statement by Third Party	https://www.sec.gov/Archives/edgar/data/1628738/000119312520003102/0001193125-20-003102-index.htm
2020-01-07	SC 14D9/A	Solicitation, recommendation statements	https://www.sec.gov/Archives/edgar/data/1628738/000119312520003112/0001193125-20-003112-index.htm
2020-01-15	SC TO-T/A	Tender offer statement by Third Party	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007546/0001193125-20-007546-index.htm
2020-01-15	SC 14D9/A	Solicitation, recommendation statements	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007558/0001193125-20-007558-index.htm
2020-01-15	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007673/0001193125-20-007673-index.htm
2020-01-15	S-8 POS	Securities to be offered to employees in employee benefit plans, post-effective amendments	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007862/0001193125-20-007862-index.htm
2020-01-15	S-8 POS	Securities to be offered to employees in employee benefit plans, post-effective amendments	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007864/0001193125-20-007864-index.htm
2020-01-15	S-8 POS	Securities to be offered to employees in employee benefit plans, post-effective amendments	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007867/0001193125-20-007867-index.htm
2020-01-15	S-8 POS	Securities to be offered to employees in employee benefit plans, post-effective amendments	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007870/0001193125-20-007870-index.htm
2020-01-15	POS AM	Post-Effective amendments for registration statement	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007884/0001193125-20-007884-index.htm
2020-01-15	POS AM	Post-Effective amendments for registration statement	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007888/0001193125-20-007888-index.htm
2020-01-15	POSASR	Post-effective Amendment to an automatic shelf registration statement	https://www.sec.gov/Archives/edgar/data/1628738/000119312520007892/0001193125-20-007892-index.htm
2020-01-27	15-12B	Securities registration termination [Section 12(b)]	https://www.sec.gov/Archives/edgar/data/1628738/000119312520014917/0001193125-20-014917-index.htm
2018-09-20	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118051837/0001209191-18-051837-index.htm
2018-09-24	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052076/0001209191-18-052076-index.htm
2018-09-26	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2018-10-02	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053463/0001209191-18-053463-index.htm
2018-10-02	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-02	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-11-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059054/0001209191-18-059054-index.htm
2018-11-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059058/0001209191-18-059058-index.htm
2018-11-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059059/0001209191-18-059059-index.htm
2018-12-10	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118061791/0001209191-18-061791-index.htm
2018-12-27	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919118064210/0001209191-18-064210-index.htm
2019-01-04	3	Initial statement of beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119002030/0001209191-19-002030-index.htm
2019-01-04	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119002033/0001209191-19-002033-index.htm
2019-01-25	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119005437/0001209191-19-005437-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008662/0001209191-19-008662-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008664/0001209191-19-008664-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008665/0001209191-19-008665-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008667/0001209191-19-008667-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008669/0001209191-19-008669-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008671/0001209191-19-008671-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008673/0001209191-19-008673-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008676/0001209191-19-008676-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008678/0001209191-19-008678-index.htm
2019-02-08	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008709/0001209191-19-008709-index.htm
2019-02-27	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014072/0001209191-19-014072-index.htm
2019-02-27	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014074/0001209191-19-014074-index.htm
2019-03-27	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119021433/0001209191-19-021433-index.htm
2019-04-01	3	Initial statement of beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119022055/0001209191-19-022055-index.htm
2019-04-01	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119022056/0001209191-19-022056-index.htm
2019-05-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119030040/0001209191-19-030040-index.htm
2019-06-07	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119035578/0001209191-19-035578-index.htm
2019-06-07	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119035584/0001209191-19-035584-index.htm
2019-06-07	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119035586/0001209191-19-035586-index.htm
2019-06-07	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119035588/0001209191-19-035588-index.htm
2019-06-26	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2019-07-17	3	Initial statement of beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119042376/0001209191-19-042376-index.htm
2019-07-17	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119042379/0001209191-19-042379-index.htm
2019-08-14	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119046001/0001209191-19-046001-index.htm
2019-09-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119048876/0001209191-19-048876-index.htm
2019-09-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119048879/0001209191-19-048879-index.htm
2019-09-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119048882/0001209191-19-048882-index.htm
2019-09-25	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119050729/0001209191-19-050729-index.htm
2019-11-12	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119056113/0001209191-19-056113-index.htm
2019-12-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119059739/0001209191-19-059739-index.htm
2019-12-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119059742/0001209191-19-059742-index.htm
2019-12-09	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119059743/0001209191-19-059743-index.htm
2019-12-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060727/0001209191-19-060727-index.htm
2019-12-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm
2019-12-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060729/0001209191-19-060729-index.htm
2019-12-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060730/0001209191-19-060730-index.htm
2019-12-16	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060731/0001209191-19-060731-index.htm
2019-12-27	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919119062016/0001209191-19-062016-index.htm
2020-01-10	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003110/0001209191-20-003110-index.htm
2020-01-10	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003111/0001209191-20-003111-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003426/0001209191-20-003426-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003427/0001209191-20-003427-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003428/0001209191-20-003428-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003429/0001209191-20-003429-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003430/0001209191-20-003430-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003431/0001209191-20-003431-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003432/0001209191-20-003432-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003433/0001209191-20-003433-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003434/0001209191-20-003434-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003435/0001209191-20-003435-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003436/0001209191-20-003436-index.htm
2020-01-15	4	Statement of changes in beneficial ownership of securities	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003437/0001209191-20-003437-index.htm
2020-01-15	25-NSE	Notification filed by national security exchange to report the removal from listing and registration of matured, redeemed or ret	https://www.sec.gov/Archives/edgar/data/1628738/000135445720000014/0001354457-20-000014-index.htm
2018-10-05	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459018023997/0001564590-18-023997-index.htm
2018-10-11	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459018024150/0001564590-18-024150-index.htm
2018-11-06	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459018027422/0001564590-18-027422-index.htm
2018-11-06	S-8	Securities to be offered to employees in employee benefit plans	https://www.sec.gov/Archives/edgar/data/1628738/000156459018027496/0001564590-18-027496-index.htm
2018-11-07	10-Q	Quarterly report [Sections 13 or 15(d)]	https://www.sec.gov/Archives/edgar/data/1628738/000156459018027601/0001564590-18-027601-index.htm
2019-02-27	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459019004901/0001564590-19-004901-index.htm
2019-03-01	10-K	Annual report [Section 13 and 15(d), not S-K Item 405]	https://www.sec.gov/Archives/edgar/data/1628738/000156459019005838/0001564590-19-005838-index.htm
2019-04-08	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459019010968/0001564590-19-010968-index.htm
2019-04-26	DEF 14A	Other definitive proxy statements	https://www.sec.gov/Archives/edgar/data/1628738/000156459019013369/0001564590-19-013369-index.htm
2019-04-26	DEFA14A	Additional definitive proxy soliciting materials and Rule 14(a)(12) material	https://www.sec.gov/Archives/edgar/data/1628738/000156459019013370/0001564590-19-013370-index.htm
2019-05-01	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000156459019014708/0001564590-19-014708-index.htm
2019-05-07	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019006048/0001628280-19-006048-index.htm
2019-05-08	10-Q	Quarterly report [Sections 13 or 15(d)]	https://www.sec.gov/Archives/edgar/data/1628738/000162828019006182/0001628280-19-006182-index.htm
2019-05-13	S-8	Securities to be offered to employees in employee benefit plans	https://www.sec.gov/Archives/edgar/data/1628738/000162828019006595/0001628280-19-006595-index.htm
2019-05-29	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019007304/0001628280-19-007304-index.htm
2019-06-07	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019007731/0001628280-19-007731-index.htm
2019-06-28	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019008451/0001628280-19-008451-index.htm
2019-08-06	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019010123/0001628280-19-010123-index.htm
2019-08-07	10-Q	Quarterly report [Sections 13 or 15(d)]	https://www.sec.gov/Archives/edgar/data/1628738/000162828019010206/0001628280-19-010206-index.htm
2019-08-23	8-K/A	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019011147/0001628280-19-011147-index.htm
2019-10-09	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019012219/0001628280-19-012219-index.htm
2019-11-07	8-K	Current report	https://www.sec.gov/Archives/edgar/data/1628738/000162828019013653/0001628280-19-013653-index.htm
2019-11-07	10-Q	Quarterly report [Sections 13 or 15(d)]	https://www.sec.gov/Archives/edgar/data/1628738/000162828019013717/0001628280-19-013717-index.htm
2020-01-17	EFFECT	Notice of Effectiveness	https://www.sec.gov/Archives/edgar/data/1628738/999999999520000113/9999999995-20-000113-index.htm
2020-01-17	EFFECT	Notice of Effectiveness	https://www.sec.gov/Archives/edgar/data/1628738/999999999520000116/9999999995-20-000116-index.htm

(BOLD) Insider Transactions:

Here you will find a list of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of (BOLD). Company insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise.
Insider Ownership: < 1%
Institutional Ownership: < 1%

Transaction Date	Insider Name	Insider Title	Type	Shares Number	Shares Price	Total Transaction	Shares Held After Transaction	Link
2018-09-28	JOHN T. GRAY	SVP, Chief Scientific Officer	Sell	87.00	40.00	3,480.00	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053463/0001209191-18-053463-index.htm
2019-03-25	LOUIS G LANGE	Director	Sell	558.00	35.94	20,054.69	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119021433/0001209191-19-021433-index.htm
2018-09-18	Matthew R Patterson	Chief Executive Officer	Sell	12,952.00	40.00	518,080.00	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118051837/0001209191-18-051837-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	4,699.00	35.60	167,283.46	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	200.00	36.32	7,263.00	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	3,900.00	37.82	147,512.43	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	1,101.00	38.85	42,777.48	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	100.00	39.52	3,952.00	0.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	100.00	0.79	79.00	100.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	1,101.00	0.79	869.79	1,101.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2019-11-08	Matthew R Patterson	Chief Executive Officer	Sell	14,426.00	30.00	432,780.00	113,394.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119056113/0001209191-19-056113-index.htm
2019-08-12	Matthew R Patterson	Chief Executive Officer	Sell	1,000.00	34.53	34,525.00	115,368.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119046001/0001209191-19-046001-index.htm
2019-08-12	Matthew R Patterson	Chief Executive Officer	Sell	19,000.00	34.02	646,309.70	116,368.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119046001/0001209191-19-046001-index.htm
2019-02-06	Matthew R Patterson	Chief Executive Officer	Buy	63,700.00			118,700.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008709/0001209191-19-008709-index.htm
2019-02-25	Matthew R Patterson	Chief Executive Officer	Sell	17,000.00	30.00	510,000.00	118,700.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014072/0001209191-19-014072-index.htm
2019-02-25	Matthew R Patterson	Chief Executive Officer	Buy	4,000.00	2.19	8,760.00	122,700.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014072/0001209191-19-014072-index.htm
2019-11-08	Matthew R Patterson	Chief Executive Officer	Buy	14,426.00	9.50	137,047.00	127,820.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119056113/0001209191-19-056113-index.htm
2018-09-18	Matthew R Patterson	Chief Executive Officer	Buy	12,952.00	2.19	28,364.88	12,952.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118051837/0001209191-18-051837-index.htm
2019-08-12	Matthew R Patterson	Chief Executive Officer	Buy	20,000.00	9.50	190,000.00	135,368.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119046001/0001209191-19-046001-index.htm
2019-02-25	Matthew R Patterson	Chief Executive Officer	Buy	17,000.00	0.78	13,260.00	135,700.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014072/0001209191-19-014072-index.htm
2019-12-23	LOUIS G LANGE	Director	Sell	1,000.00	59.60	59,596.30	13,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119062016/0001209191-19-062016-index.htm
2019-09-23	LOUIS G LANGE	Director	Sell	1,000.00	32.18	32,182.00	14,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119050729/0001209191-19-050729-index.htm
2018-09-24	Matthew R Patterson	Chief Executive Officer	Buy	15,000.00	0.78	11,700.00	15,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052076/0001209191-18-052076-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Sell	8,078.00	37.70	304,572.91	15,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Sell	5,330.00	38.04	202,731.88	15,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Sell	5,448.00	38.58	210,162.05	15,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Sell	2,144.00	39.14	83,905.44	15,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	1,000.00	37.27	37,267.00	1,558.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2019-06-24	LOUIS G LANGE	Director	Sell	200.00	39.46	7,892.00	15,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2019-06-24	LOUIS G LANGE	Director	Sell	800.00	37.89	30,308.80	15,878.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2020-01-08	Matthew R Patterson	Chief Executive Officer	Buy	64,751.00	0.78	50,505.78	163,671.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003110/0001209191-20-003110-index.htm
2019-03-25	LOUIS G LANGE	Director	Sell	1,000.00	36.00	36,003.70	16,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119021433/0001209191-19-021433-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Buy	2,144.00	0.78	1,672.32	17,144.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2019-12-12	Natalie C. Holles	President and COO	Buy	74,117.00	15.26	1,131,025.42	171,581.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm
2018-12-24	LOUIS G LANGE	Director	Sell	1,000.00	18.70	18,701.00	17,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118064210/0001209191-18-064210-index.htm
2020-01-08	Thomas P Soloway	Executive Vice President, CFO	Buy	144,669.00	2.76	399,995.32	177,165.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003111/0001209191-20-003111-index.htm
2019-12-12	Natalie C. Holles	President and COO	Buy	6,891.00	27.39	188,744.49	178,472.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm
2019-02-06	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	17,500.00			18,236.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008671/0001209191-19-008671-index.htm
2019-02-25	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	10,000.00	30.06	300,553.00	18,236.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014074/0001209191-19-014074-index.htm
2019-05-13	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	54.00	37.72	2,036.88	18,236.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119030040/0001209191-19-030040-index.htm
2019-05-13	SUYASH PRASAD	Senior VP & Chief Med Officer	Sell	9,946.00	36.98	367,761.31	18,290.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119030040/0001209191-19-030040-index.htm
2020-01-08	Thomas P Soloway	Executive Vice President, CFO	Buy	6,219.00	15.26	94,901.94	183,384.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003111/0001209191-20-003111-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	1,000.00	37.27	37,266.00	18,678.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2019-12-12	Natalie C. Holles	President and COO	Buy	14,895.00	24.74	368,502.30	193,367.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	200.00	0.79	158.00	200.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Buy	5,330.00	0.78	4,157.40	20,330.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Buy	5,448.00	0.78	4,249.44	20,448.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2018-10-01	Matthew R Patterson	Chief Executive Officer	Buy	8,078.00	0.78	6,300.84	23,078.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053466/0001209191-18-053466-index.htm
2019-02-06	Thomas P Soloway	Executive Vice President, CFO	Buy	23,333.00			23,333.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008678/0001209191-19-008678-index.htm
2020-01-08	Matthew R Patterson	Chief Executive Officer	Buy	74,297.00	2.19	162,710.43	237,968.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003110/0001209191-20-003110-index.htm
2020-01-08	Matthew R Patterson	Chief Executive Officer	Buy	11,824.00	9.50	112,328.00	249,792.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003110/0001209191-20-003110-index.htm
2020-01-08	Matthew R Patterson	Chief Executive Officer	Buy	11,666.00	15.26	178,023.16	261,458.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919120003110/0001209191-20-003110-index.htm
2019-12-23	LOUIS G LANGE	Director	Sell	10,000.00	59.60	595,993.00	265,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119062016/0001209191-19-062016-index.htm
2019-09-23	LOUIS G LANGE	Director	Sell	245.00	32.66	8,002.39	275,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119050729/0001209191-19-050729-index.htm
2019-09-23	LOUIS G LANGE	Director	Sell	9,755.00	32.15	313,613.50	276,044.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119050729/0001209191-19-050729-index.htm
2019-02-25	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	10,000.00	0.79	7,900.00	28,236.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119014074/0001209191-19-014074-index.htm
2019-05-13	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	10,000.00	0.79	7,900.00	28,236.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119030040/0001209191-19-030040-index.htm
2019-06-24	LOUIS G LANGE	Director	Sell	600.00	40.00	23,998.50	285,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2019-06-24	LOUIS G LANGE	Director	Sell	3,602.00	38.15	137,409.46	286,399.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2019-06-24	LOUIS G LANGE	Director	Sell	15,798.00	37.60	594,004.80	290,001.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119039082/0001209191-19-039082-index.htm
2019-07-15	Edward R. Conner	SVP, Chief Medical Officer	Buy	30,000.00			30,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119042379/0001209191-19-042379-index.htm
2019-03-25	LOUIS G LANGE	Director	Sell	300.00	36.64	10,992.18	305,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119021433/0001209191-19-021433-index.htm
2019-03-25	LOUIS G LANGE	Director	Sell	19,700.00	35.99	709,022.70	306,099.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119021433/0001209191-19-021433-index.htm
2018-01-03	Eric Mosbrooker	SVP, Chief Commercial Officer	Buy	31,500.00			31,800.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119002033/0001209191-19-002033-index.htm
2018-12-24	LOUIS G LANGE	Director	Sell	10,000.00	18.50	184,951.00	32,343.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118064210/0001209191-18-064210-index.htm
2018-12-24	LOUIS G LANGE	Director	Sell	20,000.00	18.67	373,434.00	325,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118064210/0001209191-18-064210-index.htm
2019-01-24	Natalie C. Holles	President and COO	Buy	8,300.00	2.76	22,948.67	33,390.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119005437/0001209191-19-005437-index.htm
2018-11-15	LOUIS G LANGE	Director	Sell	20,000.00	22.49	449,800.00	345,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059054/0001209191-18-059054-index.htm
2018-11-15	LOUIS G LANGE	Director	Sell	4,000.00	22.49	89,960.00	3,555.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059054/0001209191-18-059054-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	200.00	37.76	7,551.00	365,799.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	19,800.00	37.35	739,510.20	365,999.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2019-03-28	Mark A Meltz	SVP, General Counsel	Buy	37,333.00			37,333.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119022056/0001209191-19-022056-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	3,900.00	0.79	3,081.00	3,900.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	10,000.00	37.45	374,536.00	42,343.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2018-10-01	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	4,699.00	0.79	3,712.21	4,699.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053468/0001209191-18-053468-index.htm
2019-12-12	Thomas P Soloway	Executive Vice President, CFO	Buy	41,321.00	2.76	114,248.43	53,954.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060731/0001209191-19-060731-index.htm
2018-12-06	Matthew R Patterson	Chief Executive Officer	Buy	40,000.00	0.78	31,200.00	55,000.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118061791/0001209191-18-061791-index.htm
2018-12-24	LOUIS G LANGE	Director	Sell	1,000.00	18.71	18,713.00	558.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118064210/0001209191-18-064210-index.htm
2019-02-06	Natalie C. Holles	President and COO	Buy	23,333.00			56,723.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119008664/0001209191-19-008664-index.htm
2018-11-15	MARY NEWMAN	SVP, Regulatory Affairs	Buy	660.00	19.64	12,959.10	660.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059059/0001209191-18-059059-index.htm
2018-11-15	SUYASH PRASAD	Senior VP & Chief Med Officer	Buy	736.00	19.64	14,451.36	736.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118059058/0001209191-18-059058-index.htm
2018-09-24	LOUIS G LANGE	Director	Sell	1,000.00	37.25	37,250.30	7,555.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118052368/0001209191-18-052368-index.htm
2018-09-28	JOHN T. GRAY	SVP, Chief Scientific Officer	Buy	87.00	1.05	91.35	87.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919118053463/0001209191-18-053463-index.htm
2019-12-12	Natalie C. Holles	President and COO	Buy	45,726.00	2.76	126,427.82	91,749.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm
2019-12-12	Natalie C. Holles	President and COO	Buy	5,715.00	9.50	54,285.64	97,464.00	https://www.sec.gov/Archives/edgar/data/1628738/000120919119060728/0001209191-19-060728-index.htm

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